Sequence submission tools



Information for users of BiSSAP  (version 1.2 or earlier)

The occasional problems reported earlier for older versions of BiSSAP have been resolved in new BiSSAP version 1.3. Users are strongly recommended to use only this new version 1.3 of BiSSAP.

About BiSSAP

BiSSAP is a computer program designed to facilitate the creation of sequence listings for patent applications containing biological sequences (see Rule 30 EPC, Rule 5.2 PCT, and the Decision of the President and Notice from the EPO dated 28 April 2011 (OJ EPO 6/2011, 372 ff.)).

It has been developed by the European Patent Office in collaboration with national patent offices and the European Bioinformatics Institute.

BiSSAP can be used to prepare and verify sequences, generate the sequence listing files for submission, import existing sequence listings in WIPO ST. 25 and convert between sequence listing formats (WIPO ST. 25 and XML proposal). It also contains a "batch verification" module allowing users to verify collections of sequence listings.

Patent sequence data:

You can access published patent sequence data and other published patent data resources in life sciences via the EBI's website.

System requirements:

BiSSAP will run on the following operating systems:

  • Windows XP/Vista/7
  • Mac OS X (10.5.5 or higher, 10.6.1 or higher)
  • Linux (with GTK libraries)

Your workstation must also meet the following technical requirements:

  • 1 GB RAM (recommended: 2 GB)
  • 100 MB disk space for installation, with additional disk space for data
  • screen resolution 1280x900 (recommended: 1680x1200 or higher)
  • Java 6 JRE installed

BiSSAP is a desktop application which does not require an internet connection.  However, taxonomies and certain help pages are updated automatically if the workstation is connected to the internet.

Please contact us with any questions you may have.


PatentIn is a computer program designed to help you prepare patent applications containing nucleic acid and amino acid sequences. For details and downloads, visit the USPTO website.

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