https://www.epo.org/en/news-events/news/filing-large-sequence-listings

Filing of large sequence listings

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 test tube and symbols associated with chemistry/biotechnology

​​A revised decision and an accompanying notice explain how users should file large sequence listings, including on physical data carriers if necessary. ​ 

​​As part of the ongoing digital transformation of the European patent grant procedure, the President’s decision on the filing of sequence listings has been updated, with a view to clarifying the procedure and reassuring applicants. For some patent applications in the field of biotechnology, the associated sequence listings may be so large as to exceed the normal upload limits for filing electronically. Therefore, physical data carriers for such sequence listings, although rarely used, are still permitted despite the decommissioning of Online Filing (OLF) at the end of 2025 in favour of OLF2.0.

​Accordingly, users may exceptionally continue to use accepted data carriers if the XML sequence listing, filed either as part of the application or for search purposes, exceeds the maximum upload size of the EPO’s filing tools, which is at present 50 MB. The President’s decision as well as the accompanying notice provide further details on the accepted data carriers, notably USB sticks, CD-ROMs and DVDs.