Invention: Microchip for quick DNA testing
Unravelling the complexities of the human genome was once an endeavour reserved for the scientific elite, but Christofer Toumazou’s invention – a USB stick that decodes a patient’s DNA within minutes – puts that unique ability at people’s fingertips.
The British scientist’s invention employs small silicon microchips that can identify genetic mutations that determine a person’s predispositions to certain hereditary diseases. These portable, low-power devices can analyse data on the spot rather than in a lab environment. As such, they represent a great stride in medicine as emphasis shifts from treating illnesses to preventing and diagnosing them in a targeted manner.
The tests take the form of a so-called “lab on a chip” – organic semiconductors and sensors that use very small amounts of chemicals to conduct tests on the spot. The chip can then be inserted into a USB stick and provide results that are viewable on a computer within 20 minutes.
Societal benefit
Not only does Christofer Toumazou’s invention make DNA testing more economical for clinics and hospitals that once had to spend upwards of half a million US dollars on conventional DNA-sequencing machines, it also provides patients with results within minutes rather than weeks. Its cost-efficiency could be particularly appealing in countries where there are few healthcare resources, such as in sub-Saharan Africa, where poorly equipped clinics could now perform diagnostic tests without the support of laboratories.
Economic benefit
The market potential for DNA sequencing is immense. By 2016, it is expected to be worth US $6.6 billion and grow by 17.5% annually – a rate that is compounded by the emergence of breakthrough technologies such as Christofer Toumazou’s cost-efficient application for testing DNA. The dynamic is fuelled by advances in bioinformatics, in imaging, in nanotechnology and in microfluidics as well as – in the case of Toumazou’s company DNA Electronics – in microelectronics.
DNA Electronics has entered in various collaborations, amongst which were Roche and Pfizer. The firm actively licenses-out its patents as its business strategy. Current licensees include Life Technologies, Roche, the National Institute for Health Research NHS, and GENEU.