The examination fee is due when the request for examination is filed. Since the latter is contained in the prescribed form for the request for grant (Form 1001), the examination fee may be paid straight away on the date of filing of the European patent application if the application is filed with said prescribed Form 1001. It may be paid up to expiry of the period laid down in Rule 70(1), namely within six months of the date of publication of the mention of the European search report.
The designation fee falls due upon publication of the mention of the European search report. It may be paid within six months of the mentioned date of publication (Rule 39).
For Euro-PCT applications, see E‑VIII, 2.1.3.